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Cortisone Injections for Knee Osteoarthritis: Your Comprehensive FAQ

If you’re experiencing persistent knee pain due to osteoarthritis and are searching for options like a cortisone injection, you’re in the right place. Cortisone (also known as a steroid) injections can help reduce inflammation and provide pain relief. Below, you’ll find answers to common patient questions about cortisone injections, including everything from what to expect after the procedure to alternative treatments.



What Is a Cortisone Knee Joint Injection?

A cortisone injection, or steroid shot, is an anti-inflammatory treatment administered into or around a joint, most commonly the knee, to alleviate swelling and pain. This procedure is particularly beneficial for patients with knee osteoarthritis as it provides relatively quick pain relief, allowing patients to return to daily activities with more comfort.


How Long Will a Cortisone Shot Last in the Knee?

Relief duration varies from patient to patient. Some people experience symptom relief for several weeks, while others may enjoy a few months of reduced pain and inflammation. The longevity of the effect depends on factors such as the severity of osteoarthritis and activity level.

If you want to explore other types of injections (like hyaluronic acid, PRP, or Arthrosamid), check out injection therapy options for knee osteoarthritis.



Can I Walk After a Cortisone Injection in My Knee?

Yes, most patients can walk immediately following the procedure. However, it’s generally recommended to:

  • Avoid strenuous activities for at least a day or two

  • Use ice packs to reduce swelling if needed

  • Follow your healthcare provider’s specific post-injection instructions

To learn more about knee osteoarthritis and how it might affect your mobility, read Understanding Knee Osteoarthritis: Causes, Diagnosis, and Treatment Options.


Is It Worth Getting a Cortisone Shot in Your Knee?

Many patients find significant short-term relief from cortisone injections. They can be especially beneficial if you’re dealing with an acute flare-up or trying to manage pain while pursuing other treatments such as physical therapy or lifestyle modifications. That said, cortisone injections are not a cure for osteoarthritis; they are one aspect of a broader pain management strategy.



Why Do Doctors Not Like to Give Cortisone Shots?

While cortisone injections can be very effective, doctors may hesitate to administer them repeatedly because:

  • They can weaken the articular cartilage

  • Might lead to reduced effectiveness over time

  • Potential side effects, such as elevated blood sugar or local tissue changes

If you’re considering alternative treatments, explore our comparison of hyaluronic acid vs. steroid injections in knee pain.


What Is the Downside to a Cortisone Shot?

Potential downsides include:

  • Short-term increase in pain at the injection site (also known as "steroid flare")

  • Risk of infection (though low)

  • Possible negative impact on cartilage with repeated use

  • Elevated blood sugar in diabetic patients

Always discuss any underlying medical conditions with your doctor before proceeding with a cortisone shot.



What Are the Alternatives to a Cortisone Shot?

There are several emerging alternatives, including:



What are the costs of cortisone and other joint injections?

If you’re researching cortisone injection costs in Kent and London, we are here to help. At ACTIVATE Musculoskeletal Clinic, we offer transparent and affordable pricing packages. To learn more, check out our pricing overview.


What Should I Avoid After a Cortisone Shot?

  • Strenuous Exercise: Give yourself at least 24-48 hours before resuming high-impact activities.

  • Prolonged Heat Exposure: Avoid hot tubs or saunas for a day to reduce the risk of inflammation.

  • Rubbing or Massaging the Injection Site: This can increase irritation.

Your healthcare provider might recommend wearing supportive footwear or using assistive devices if you experience discomfort when walking post-injection.



Does a Cortisone Shot in the Knee Affect the Whole Body?

A single cortisone shot mainly works locally on the knee joint. However, some of the medication can enter your bloodstream, potentially causing short-term systemic effects like:

  • Slight mood changes

  • Mild increase in blood sugar levels

For most patients, these effects are minimal and resolve quickly.



Book Your Appointment Today

Ready to take the next step? Whether you’re located in Kent, London, or nearby, our expert team at ACTIVATE Musculoskeletal Clinic can help determine if a cortisone injection is the right choice for your knee osteoarthritis. We offer personalized treatment plans to help you get back to your daily activities as comfortably as possible.

Click here to book an appointment.

If you have any additional questions about cortisone injections or any other knee pain treatments, get in touch with us at ACTIVATE Musculoskeletal Clinic. We’re here to help you move better and live pain-free.


📍 ACTIVATE Musculoskeletal Clinic – Kent & London

📲 07369222132   


About the Author: Dr. Mustafa Alnaib MBChB, MRCS, MSc, FEBOT is an orthopaedic surgeon, musculoskeletal doctor and Clinic Director at ACTIVATE Musculoskeletal Clinic in Kent & London

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ACTIVATE | Musculoskeletal Clinic is the trading name for ZAF Orthopaedic Solutions Ltd

7a Boughton Parade, Loose road, Maidstone, ME15 9QD

Tel: 07369222132

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