How does Arthrosamid relieve knee pain?

Arthrosamid is a hydrogel injection that integrates into the knee joint lining, acting as a long-lasting cushion. It helps reduce friction, ease pain, and improve joint function without breaking down over time.

Am I a suitable candidate for Arthrosamid treatment?

You may be eligible for Arthrosamid if you have moderate knee osteoarthritis and have not responded well to steroid or hyaluronic acid injections. It is not suitable for patients with inflammatory arthritis or active joint infection.

What should I expect during the injection appointment?

The procedure is performed in a clinical setting using ultrasound guidance. After cleansing and numbing the area, a single Arthrosamid injection is administered into the joint space. The visit typically lasts under an hour.

How soon will I notice improvement after the injection?

Patients may begin to feel relief within a few weeks, with clinical studies showing continued benefit up to three years post-injection. Improvement in pain and mobility tends to be gradual but sustained.

Are there any side effects to be aware of?

Mild swelling or discomfort at the injection site may occur temporarily. Rare side effects can include stiffness or a localised inflammatory reaction. Arthrosamid does not break down in the body and has shown a strong safety profile.

Arthrosamid Injection for Knee Osteoarthritis From ACTIVATE Clinic in London & Kent

Mustafa Alnaib
Mar 3, 2024
4 min read

Updated: Sep 17

Dr Alnaib is very patient and professional. I received injections of Arthrosamid in both knees. It’s been a month and my right knee feels 98 percent. My left knee has always been more problematic, and it still creates some pain. I have no trouble walking. I am hopeful that it will continue to improve ⭐⭐⭐⭐⭐

Understanding Knee Osteoarthritis

Osteoarthritis (OA) is a common, degenerative joint disease that primarily affects the knee, leading to pain, stiffness, and a significant reduction in quality of life. Traditional treatments have ranged from physical therapy and medications to surgical interventions in more advanced cases. Arthrosamid has emerged as a novel, non-surgical intervention designed to provide long-lasting pain relief for individuals suffering from knee OA. This innovative treatment utilises a non-biodegradable hydrogel injected into the knee joint.

What Is Arthrosamid and How Does It Work?

Arthrosamid® is an injectable, clear, hydrophilic gel that is both non-absorbable and non-biodegradable. It is composed of a solid framework of non-biodegradable polyacrylamide (2.5%) intertwined with non-pyrogenic water (97.5%).

This product is provided in six sterile, pre-filled syringes designed for single use, containing 1 mL of the gel in each syringe. This hydrogel acts as a cushion inside the joint and is designed to integrate with the tissue within the knee, providing support and reducing pain without degrading over time. The unique properties of Arthrosamid® allow it to offer both immediate and sustained relief from OA symptoms, making it an attractive option for those seeking alternatives to traditional therapies.

Is Arthrosamid Right for Me?

This treatment may be ideal for you if:

✅ You've already tried steroid or hyaluronic acid injections without lasting relief

✅ You're looking for a solution to avoid or delay knee replacement surgery

✅ You want long-term pain relief with a single injection

✅ You prefer a treatment that doesn't require repeated appointments

✅ You're active and want to stay mobile without downtime

✅ You value precision and safety with ultrasound-guided care by an experienced doctor

The Arthrosamid® Knee Injection Procedure at ACTIVATE in London

The injection procedure is minimally invasive and typically conducted in an outpatient setting by an experienced doctor. It involves an ultrasound guided injection of Arthrosamid® directly into the intra-articular space of the knee. The procedure is quick, does not require hospitalisation, and patients can usually resume normal activities shortly afterward. The simplicity and safety of the procedure make it an appealing option for many patients.

Benefits and Efficacy

Arthrosamid® has been shown to provide significant pain relief within four weeks post-injection, with the effects sustained over a period of 156 weeks in clinical trials. This long-term relief is a key advantage of Arthrosamid® over other injectable treatments for OA, which may require more frequent administration. The hydrogel's safety and efficacy are supported by over two decades of research and development, along with clinical trials that document its positive impact on patients' pain levels and mobility.

✅ Long-lasting pain relief

✅ Reduced stiffness and improved mobility

✅ Decreased need for pain medications or repeated injections

✅ Improved quality of life for those with moderate knee OA

Safety and Considerations

As with any medical procedure, there are potential risks and considerations associated with Arthrosamid® injections. However, the hydrogel has been extensively tested for biocompatibility and safety, with a very low incidence of adverse effects reported. It is crucial for patients to discuss their individual medical history and potential risks with their healthcare provider before proceeding with the treatment.

✅ Minimal side effects reported in trials

✅ Does not degrade over time, reducing risk of re-injection complications

✅ No known systemic effects

Possible Side Effects:

Mild swelling or discomfort at the injection site (temporary)
Very rare: joint stiffness or a local inflammatory reaction

Who Should Avoid Arthrosamid?

Patients with an active joint inflammation, Rheumatoid Arthritis, Gout and Psoriatic Arthritis.
Patients allergic to any component of the hydrogel (rare)

Before receiving the injection, you will be thoroughly assessed by Dr Alnaib to ensure this treatment is appropriate for your individual medical history and condition severity.

Read ACTIVATE's Arthrosamid comprehensive resources:

What are the differences between Arthrosamid and Hyaluronic Acid?

Arthrosamid FAQs

Cost of Knee Injections in London & Kent

ACTIVATE Your Journey to Knee Pain Relief

Arthrosamid® offers a promising new avenue for managing knee osteoarthritis, providing a safe, effective, and long-lasting alternative to traditional treatments. Patients struggling with OA symptoms are encouraged to explore this option further with their healthcare provider. You can also check which knee injection may be suitable for you using ACTIVATE's free digital tool.

For those interested in learning more about Arthrosamid Knee Injection, booking a consultation at ACTIVATE Musculoskeletal Clinic in London Harley Street with Dr Alnaib can be the first step towards managing their knee osteoarthritis more effectively. Patients can find more detailed information and schedule a consultation through the clinic's website

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This comprehensive exploration of Arthrosamid® for knee osteoarthritis aims to inform and empower patients considering this treatment option. Remember, the decision to proceed with any medical treatment should always be made in consultation with a qualified healthcare provider to ensure it aligns with your individual health needs and circumstances.

About the Author: Dr. Mustafa Alnaib MBChB, MRCS, MSc, FEBOT is an orthopaedic surgeon, musculoskeletal doctor and Clinic Director at ACTIVATE Musculoskeletal Clinic in Kent